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KMID : 1101220000320030205
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2000 Volume.32 No. 3 p.205 ~ p.213
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Investigation for the Enzyme Immunoassay in Hepatitis C
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Chang Soon-Mo
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Abstract
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Most of posttransfusion hepatitis will be developed by hepatitis C virus. So the ultimate goal of blood donor screening of anti HCV antibodies is specific exclusion of viral carrier from the blood donor population. To evaluate whether various enzymatic immunoassay for anti HCV antibodies are an useful methods to rule out viral carrier or not, the author investigated the sensitivity and specificity of various 2nd generation anti HCV reagent. There were noticed some false positive and false negative by different reagent and also demonstrated same results with control sample confirmed by RT-PCR. From these results it is suggested that 3rd generation anti HCV antibody should be adopted for screening of donor blood.
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KEYWORD
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anti HCV, EIA, 3rd generation anti HCV
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